Ongoing control of students’ knowledge can be carried out in various forms, including gaming. The article presents the experience of using a quiz game in the discipline «Biochemistry» for students of a medical university. The quiz scenario is presented, which includes the round structure and task examples, as well as an algorithm for assessing students' knowledge. The article presents an analysis of the students’ survey on satisfaction with the quiz use in the educational process, which revealed both the positive and negative sides of conducting ongoing control in a playful way. The team format of the game eliminates the use of ready-made answers and the cheating factor, but does not allow an objective assessment of the individual level of knowledge of each participant. At the same time, this form of knowledge assessment provides quick feedback and makes the learning process more dynamic and interesting, helping to increase students’ motivation.